Tazocin

Aka. PipTaz, Piperacillin-Tazobactam, Vitamin T

CLASS

  • broad spectrum penicillin + beta-lactamase
  • Tazocin =  piperacillin-tazobactam

MECHANISM OF ACTION

  • bacterial cell wall inhibition

PHARMACEUTICS

  • reconstitute with H2O
  • give as slow push

DOSE

  • 4.5g Q8hrly
  • 4g of piperacillin + 500mg of tazobactam
  • 50-75mg/kg Q 6-8hrly

INDICATIONS

  • aerobic gram positive bacteria
  • aerobic gram negative bacteria
  • anaerobes

ADVERSE EFFECTS

  • hypersensitivity
  • seizures
  • myoclonus

PHARMACOKINETICS

  • Absorption
  • Distribution
  • Metabolism
  • Elimination

CCC Pharmacology Series

Critical Care

Compendium

Chris is an Intensivist and ECMO specialist at The Alfred ICU, where he is Deputy Director (Education). He is a Clinical Adjunct Associate Professor at Monash University, the Lead for the  Clinician Educator Incubator programme, and a CICM First Part Examiner.

He is an internationally recognised Clinician Educator with a passion for helping clinicians learn and for improving the clinical performance of individuals and collectives. He was one of the founders of the FOAM movement (Free Open-Access Medical education) has been recognised for his contributions to education with awards from ANZICS, ANZAHPE, and ACEM.

His one great achievement is being the father of three amazing children.

On Bluesky, he is @precordialthump.bsky.social and on the site that Elon has screwed up, he is @precordialthump.

| INTENSIVE | RAGE | Resuscitology | SMACC

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