Ventriculomegaly is due to cerebral atrophy (e.g., Parkinson disease) or increased cerebrospinal fluid (CSF) within the ventricles.
Increased CSF is due to:
- Increased CSF production (e.g., choroid-plexus papilloma), or
- Impaired CSF re-absorption (e.g., subarachnoid-villi inflammation), or
- Obstruction of CSF flow (e.g., non-communicating hydrocephalus)
Congenital causes of ventriculomegaly
- Neural tube defect (e.g, myelomeningocele)
- Aquaductal stenosis
- CNS malformation (e.g., Dandi-Walker syndrome)
- Intrauterine infection (e.g., CMV, rubella, etc.)
Acquired causes of ventriculomegaly
- Paget disease (obstruction of CSF flow)
- Bacterial or viral meningitis (impaired CSF absorption)
- Tumor (obstruction of CSF flow)
- Post-hemorrhagic (e.g., trauma, aneurysmal rupture, AVM, coagulopathy) impaired absorption and/or obstruction of flow
References and Links
Social media and other web resources
- UMEM Education Pearls — What’s the Diagnosis? Case submitted by Bethany Radin
Chris is an Intensivist and ECMO specialist at the Alfred ICU in Melbourne. He is also a Clinical Adjunct Associate Professor at Monash University. He is a co-founder of the Australia and New Zealand Clinician Educator Network (ANZCEN) and is the Lead for the ANZCEN Clinician Educator Incubator programme. He is on the Board of Directors for the Intensive Care Foundation and is a First Part Examiner for the College of Intensive Care Medicine. He is an internationally recognised Clinician Educator with a passion for helping clinicians learn and for improving the clinical performance of individuals and collectives.
After finishing his medical degree at the University of Auckland, he continued post-graduate training in New Zealand as well as Australia’s Northern Territory, Perth and Melbourne. He has completed fellowship training in both intensive care medicine and emergency medicine, as well as post-graduate training in biochemistry, clinical toxicology, clinical epidemiology, and health professional education.
He is actively involved in in using translational simulation to improve patient care and the design of processes and systems at Alfred Health. He coordinates the Alfred ICU’s education and simulation programmes and runs the unit’s education website, INTENSIVE. He created the ‘Critically Ill Airway’ course and teaches on numerous courses around the world. He is one of the founders of the FOAM movement (Free Open-Access Medical education) and is co-creator of litfl.com, the RAGE podcast, the Resuscitology course, and the SMACC conference.
His one great achievement is being the father of three amazing children.
On Twitter, he is @precordialthump.